Biotechnological production of chiral acetoin
Websignificantly higher biocatalytic efficiency in terms of the production of chiral acetoin and (2S,3S)-2,3-butanediol. The application of this coexpression system to the production of other chiral chemicals could be extended by using different NAD(P)-dependent dehydrogenases that require NAD(P)+ for catalysis. WebJan 1, 1993 · Biotechnological production of chiral acetoin. 2024, Trends in Biotechnology. Show abstract. Acetoin (AC) is an important platform bulk chemical with versatile applications. It exists in two stereoisomeric forms: (3R)-AC and (3S)-AC. Both stereoisomers could be potentially applied in the pharmaceutical industry, agriculture, …
Biotechnological production of chiral acetoin
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WebJul 1, 2024 · Biotechnological production of chiral acetoin 2024, Trends in Biotechnology Show abstract Efficient acetoin production from pyruvate by engineered Halomonas bluephagenesis whole-cell biocatalysis 2024, Frontiers of Chemical Science and Engineering Development of an industrial yeast strain for efficient production of 2,3 … WebFeb 21, 2024 · Meng W, Ma C, Xu P, Gao C. Biotechnological production of chiral acetoin. Trends Biotechnol. 2024;40(8):958–73. ... Li L, Wei XT, Yu WP, Wen ZY, Chen …
WebAcetoin and 2,3-butanediol (2,3-BD) have a large number of industrial applications. The production of acetoin and 2,3-BD has traditionally relied on oil supplies. Microbial production of acetoin and 2,3-BD will alleviate the dependence on oil. Acetoin and 2,3-BD are neighboring metabolites in the 2,3-BD metabolic pathway of bacteria. WebAcetoin is a high-value-added industrial product and a promising bio-based platform chemical. The two chiral enantiomers of acetoin are important potential pharmaceutical intermediates. However, at present it is very expensive to produce optically pure acetoin using conventional chemical synthesis methods.
WebDec 13, 2024 · As an important flavor and chiral platform chemical, acetoin is widely used in the pharmaceutical, chemical and food industries, and can be obtained by chemical synthesis and microbial fermentation (Xiao and Lu 2014).Owing to well-known shortcomings of conventional chemical synthesis, increasing attention is being paid to … WebSep 16, 2024 · In a fermentation medium containing 100 g L⁻¹ glucose and 200 g L⁻¹ hydrolysate, Bacillus sp. H-18W produced 21.84 g L⁻¹ acetoin with an ee value of 96.25% at 60 h. This is the first report of...
WebDec 13, 2024 · The growing need for industrial production of bio-based acetoin and 2,3-butanediol (2,3-BD) is due to both environmental concerns, and their widespread use in the food, pharmaceutical, and chemical industries. Acetoin is a common spice added to many foods, but also a valuable reagent in many chemical syntheses. Similarly, 2,3-BD is an …
WebJun 1, 2013 · Biotechnological production of chiral acetoin 2024, Trends in Biotechnology Show abstract Highly efficient synthesis of pharmaceutically relevant chiral 3-N-substituted-azacyclic alcohols using two enantiocomplementary short chain dehydrogenases 2024, Biochemical Engineering Journal Show abstract howard crowhurstWebFeb 21, 2024 · Meng W, Ma C, Xu P, Gao C. Biotechnological production of chiral acetoin. Trends Biotechnol. 2024;40(8):958–73. ... Li L, Wei XT, Yu WP, Wen ZY, Chen SW. Enhancement of acetoin production from … how many inches is 6\u0027 10howard crossing aptWebFeb 1, 2024 · Acetoin production is mediated via acetolactate synthase and α-acetolactate decarboxylase and is considered an indirect mechanism to enhance plant … howard crossWebFeb 1, 2024 · Metabolic engineering of Escherichia coli for efficient production of (3R)-acetoin. The optimization of fermentation variables and fed-batch culture resulted in a … how many inches is 6\u0027 4WebAcetoin is an important four-carbon compound that has many applications in foods, chemical synthesis, cosmetics, cigarettes, soaps, and detergents. Its stereoisomer (S)-acetoin, a high-value chiral compound, can also be used to synthesize optically active drugs, which could enhance targeting properties and reduce side effects. Recently, … howard crossing apartment homes ellicott cityWebAug 1, 2024 · Article on Biotechnological production of chiral acetoin, published in Trends in Biotechnology 40 on 2024-08-01 by Wensi Meng+3. Read the article … how many inches is 6\u00270